Reigning champions Inter Miami CF launch the 2026 Major League Soccer season Saturday night with a high-profile road clash against Los Angeles FC at the Los Angeles Memorial Coliseum.
After an offseason filled with celebrations following their 2025 MLS Cup triumph, Miami now turns its focus to defending the title under head coach Javier Mascherano. The opener presents an immediate challenge against a dangerous LAFC side led by attacking threats Son Heung-min and Denis Bouanga, both in strong form after Concacaf Champions Cup action.
Match Details
- Kickoff: 9:30 p.m. ET / 6:30 p.m. PT
- Venue: Los Angeles Memorial Coliseum
- Competition: MLS Regular Season
- Inter Miami Form: WWLWD
Team News: Messi Returns, Reguilón Out
All eyes are on Lionel Messi, who returned to training after a minor hamstring scare in preseason and is expected to start. The Argentine superstar enters 2026 after an MVP and Golden Boot campaign and has already produced five goal contributions in three previous meetings with LAFC.
However, new left-back signing Sergio Reguilón will miss the opener with a knee injury.
Several newcomers could debut, including goalkeeper Dayne St. Clair and striker Germán Berterame, while midfield reinforcement Rodrigo De Paul begins his first full season after joining permanently in 2025.
Predicted Inter Miami Lineup (4-2-3-1)
GK: Dayne St. Clair
RB: Ian Fray
CB: Maximiliano Falcón
CB: Micael
LB: Noah Allen
DM: David Ayala
DM: Rodrigo De Paul
RW: Tadeo Allende
AM: Lionel Messi
LW: Mateo Silvetti
ST: Germán Berterame
Key Storylines to Watch
- Messi’s Impact: The Miami captain remains the league’s biggest difference-maker.
- New Signings: Berterame’s goal scoring and St. Clair’s presence in net could reshape the team.
- Early Statement Game: A road win against a Western Conference contender would reinforce Miami’s title credentials.
With a star-studded roster and confidence from last season’s success, Inter Miami enters 2026 believing it can repeat — and the journey begins in Los Angeles.
For more on this anticipated match, stay tuned to Que Onda Magazine.

